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Ropinirole

Product Name
Ropinirole
CAS No.
91374-21-9
Chemical Name
Ropinirole
Synonyms
Ropinirole base;SKF-101468;ROPINIROLE;Ropinirolum;ROPINIROLE 99%;RSYYRopinirole;Unii-030pyr8953;SKF-101468A:ReQuip;Ropinirole USP/EP/BP;Ropinirole Impurity 22
CBNumber
CB9137570
Molecular Formula
C16H24N2O
Formula Weight
260.37
MOL File
91374-21-9.mol
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Ropinirole Property

Melting point:
243-250°C
Boiling point:
410.5±45.0 °C(Predicted)
Density 
1.040±0.06 g/cm3(Predicted)
pka
14.17±0.20(Predicted)
CAS DataBase Reference
91374-21-9(CAS DataBase Reference)
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Safety

Hazardous Substances Data
91374-21-9(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Tocris
Product number
3680
Product name
Ropinirole
Purity
≥99%(HPLC)
Packaging
10
Price
$87
Updated
2021/12/16
Tocris
Product number
3680
Product name
Ropinirole
Purity
≥99%(HPLC)
Packaging
50
Price
$363
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004095
Product name
ROPINIROLE
Purity
95.00%
Packaging
10MG
Price
$612.44
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D34162
Product name
Ropinirole-d14 HCl
Packaging
1mg
Price
$625
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004095
Product name
ROPINIROLE
Purity
95.00%
Packaging
50MG
Price
$823.46
Updated
2021/12/16
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Ropinirole Chemical Properties,Usage,Production

Uses

Antiparkinsonian (D2receptor agonist).

Definition

ChEBI: Ropinirole is a member of indolones and a tertiary amine. It has a role as a dopamine agonist, an antiparkinson drug, a central nervous system drug and an antidyskinesia agent.

brand name

Requip (GlaxoSmithKline).

Synthesis Reference(s)

Journal of Medicinal Chemistry, 28, p. 1533, 1985 DOI: 10.1021/jm00148a028

Clinical Use


Anti-Parkinson agent
Restless legs syndrome (RLS)

Drug interactions

Potentially hazardous interactions with other drugs
Antipsychotics: antagonism of anti-Parkinsonian effect - avoid.
Metoclopramide: antagonism of anti-Parkinsonian effect - avoid.
Oestrogens: concentration increased.

Metabolism

Ropinirole is hepatically metabolised by the cytochrome P450 enzyme, CYP1A2, and excreted in the urine as inactive metabolites.

Ropinirole Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Ropinirole manufacturers

Hebei Mingeng Biotechnology Co., Ltd
Product
Ropinirole 91374-21-9
Price
US $200.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000kg/Month
Release date
2022-11-27
Shijiazhuang Gantuo Biotechnology Co., Ltd
Product
Ropinirole 91374-21-9
Price
US $100.00/mg
Min. Order
25mg
Purity
99%
Supply Ability
1000g
Release date
2023-03-10
Baoji Guokang Healthchem co.,ltd
Product
Ropinirole
Price
US $64.00/g
Min. Order
1g
Purity
99%
Supply Ability
10kg
Release date
2021-06-07

91374-21-9, RopiniroleRelated Search:


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  • ACTIVE PHARMACEUTICAL INGREDIENTS
  • Pharmaceutical material and intermeidates
  • Antiparkinsonian